C1orf52

Across TCGA cell cohorts, C1orf52 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,663 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C1orf52-associated GO terms across cancer lineages are Zinc ion import into Golgi lumen, Regulation of post-translational protein modification, and Regulation of protein modification by small protein conjugation or removal. Each is linked with C1orf52 in more than 10 cancer types. Because this analysis shows association rather than direction, both C1orf52-to-partner and partner-to-C1orf52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zinc ion import into Golgi lumen grouped by C1orf52-low versus C1orf52-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf52→partner) and Y-score (partner→C1orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Zinc ion import into Golgi lumen →	+0.124	+0.692	<.001	<.001	3	11
STOMACH	Regulation of post-translational protein modification →	+0.067	+0.662	.002	.003	3	10
STOMACH	Regulation of protein modification by small protein conjugation or removal →	+0.064	+0.815	.002	<.001	3	10
LUNG_NSCLC_LUSC	Negative regulation of RNA polymerase II transcription preinitiation complex assembly →	+0.109	+0.764	<.001	<.001	3	10
STOMACH	Positive regulation of post-translational protein modification →	+0.076	+0.753	.002	.006	2	10
OVARY	Negative regulation of protein ubiquitination →	+0.092	+0.652	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,663 associations by consensus.

Zinc ion import into Golgi lumen by C1orf52 expression — CNS

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