C1orf43

Across TCGA patient cohorts, C1orf43 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,041 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C1orf43-associated proteins across cancer lineages are HDGF, ZNF687, and RPRD2. Each is linked with C1orf43 in more than 7 cancer types. Because this analysis shows association rather than direction, both C1orf43-to-partner and partner-to-C1orf43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf43 versus HDGF in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf43→partner) and Y-score (partner→C1orf43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HDGF →	+0.468	+0.513	<.001	.002	3	8
LSCC	ZNF687 →	+0.412	+0.625	<.001	<.001	3	7
LSCC	RPRD2 →	+0.296	+0.503	<.001	<.001	3	7
UCEC	PRCC →	+0.360	+0.936	<.001	<.001	3	7
OV	ZNF687_S140 →	+0.522	+0.354	.003	.005	3	6
UCEC	UBE2Q1 →	+0.324	+0.834	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,041 associations by consensus.

C1orf43 vs HDGF — OV

Explore this scatter interactively →