C1orf43

Across TCGA patient cohorts, C1orf43 protein abundance is significantly associated with the RNA expression of many other genes, with 2,744 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C1orf43-associated genes across cancer lineages are TMEM125, ALDH6A1, and LEF1. Each is linked with C1orf43 in more than 2 cancer types. Because this analysis shows association rather than direction, both C1orf43-to-partner and partner-to-C1orf43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf43 versus TMEM125 in CCRCC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf43→partner) and Y-score (partner→C1orf43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TMEM125 →	+1.401	+0.259	.003	.002	3	3
GBM	ALDH6A1 →	+0.580	+0.220	<.001	.001	3	2
OV	LEF1 →	-1.257	-0.567	.002	.004	3	2
GBM	MOAP1 →	+0.462	+0.188	<.001	.002	3	2
LUAD	SLC35F3 →	+0.994	+0.357	<.001	.001	3	2
LUAD	RN7SKP245 →	-0.443	-0.271	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,744 associations by consensus.

C1orf43 vs TMEM125 — CCRCC

Explore this scatter interactively →