C1orf43

Across TCGA cell cohorts, C1orf43 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible C1orf43-associated genes across cancer lineages are OR2D3, FSCB, and FOXB2. Each is linked with C1orf43 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf43-to-partner and partner-to-C1orf43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2D3 grouped by C1orf43-low versus C1orf43-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf43→partner) and Y-score (partner→C1orf43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR2D3 →	+0.020	+4.432	<.001	.003	3	1
STOMACH	FSCB →	+0.018	+4.794	<.001	.001	3	1
STOMACH	FOXB2 →	+0.010	+4.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR2D3 by C1orf43 expression — STOMACH

Explore this box plot interactively →