C1orf226

Across TCGA pan-cancer cohorts, C1orf226 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated C1orf226 data layer compared with 27 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher C1orf226 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C1orf226 expression acts as an unfavorable survival marker.

COAD and CESC are the cancer types where C1orf226 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.142	0.871	<.001	36	view →
CESC	OS	Median	III,IV	0.068	0.756	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

C1orf226–COAD (OS)

Open the COAD breakdown →