C1orf226

Across TCGA patient cohorts, C1orf226 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,645 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C1orf226-associated proteins across cancer lineages are C1orf226_S198, C1orf226_S223, and NOS1AP. Each is linked with C1orf226 in more than 8 cancer types. Because this analysis shows association rather than direction, both C1orf226-to-partner and partner-to-C1orf226 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf226 versus C1orf226_S198 in BRCA, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf226→partner) and Y-score (partner→C1orf226) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	C1orf226_S198 →	+1.393	+2.159	<.001	<.001	3	9
BRCA	C1orf226_S223 →	+1.301	+2.166	<.001	<.001	3	9
BRCA	NOS1AP →	+1.079	+2.132	<.001	<.001	3	8
LUAD	NOS1AP_S266 →	+0.728	+1.073	<.001	<.001	3	6
COAD	C1orf35 →	+0.498	+0.671	<.001	<.001	3	6
LSCC	RPRD2 →	+0.267	+0.882	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,645 associations by consensus.

C1orf226 vs C1orf226_S198 — BRCA

Explore this scatter interactively →