Across TCGA pan-cancer cohorts, C1orf220 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated C1orf220 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher C1orf220 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C1orf220 expression acts as an unfavorable survival marker.

CESC are the cancer types where C1orf220 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	All	0.227	0.798	.002	18	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: C1orf220 tumor-vs-normal RNA expression · all C1orf220 data types