Across TCGA patient cohorts, C1orf220 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,020 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C1orf220-associated proteins across cancer lineages are ACIN1, RBBP5, and ZC3H4. Each is linked with C1orf220 in more than 5 cancer types. Because this analysis shows association rather than direction, both C1orf220-to-partner and partner-to-C1orf220 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf220→partner) and Y-score (partner→C1orf220) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ACIN1 →	+0.210	+0.340	<.001	.002	3	5
LSCC	RBBP5 →	+0.277	+0.515	<.001	<.001	3	5
BRCA	ZC3H4 →	+0.224	+0.519	.001	.007	3	5
BRCA	PHC3 →	+0.376	+0.602	<.001	<.001	3	5
OV	CCDC12 →	+0.353	+0.628	.003	.003	2	6
LSCC	DHX9 →	+0.317	+0.684	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,020 associations by consensus.

Exploration

C1orf220 survival (RNA) · tumor vs normal (RNA) · all C1orf220 data types