Across TCGA cell cohorts, C1orf220 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C1orf220-associated genes across cancer lineages are OR8B12, OR8A1, and OR10D3. Each is linked with C1orf220 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf220-to-partner and partner-to-C1orf220 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf220→partner) and Y-score (partner→C1orf220) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR8B12 →	+0.054	+4.734	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR8A1 →	+0.447	+4.212	<.001	.007	3	1
LUNG_NSCLC_LUAD	OR10D3 →	+0.119	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	OR8B3 →	+0.036	+4.371	.002	.005	3	1
LUNG_NSCLC_LUAD	OR8B2 →	+0.087	+5.189	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

C1orf220 survival (RNA) · tumor vs normal (RNA) · all C1orf220 data types