C1orf216

Across TCGA patient cohorts, C1orf216 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,570 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C1orf216-associated proteins across cancer lineages are DBN1, CLINT1, and CRTAP. Each is linked with C1orf216 in more than 5 cancer types. Because this analysis shows association rather than direction, both C1orf216-to-partner and partner-to-C1orf216 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf216 versus DBN1 in GBM, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf216→partner) and Y-score (partner→C1orf216) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DBN1 →	+0.436	+0.496	<.001	<.001	3	6
OV	CLINT1 →	-0.246	-0.495	<.001	.003	3	5
COAD	CRTAP →	+0.427	+0.560	<.001	<.001	3	5
OV	FN1 →	+0.912	+0.464	.001	.008	3	5
COAD	GPX7 →	+0.512	+0.495	<.001	<.001	3	5
CCRCC	SULF1 →	+0.818	+0.330	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,570 associations by consensus.

C1orf216 vs DBN1 — GBM

Explore this scatter interactively →