C1orf216

Across TCGA patient cohorts, C1orf216 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf216-associated genes across cancer lineages are Myocytes, Basophils, and Endothelial cells. Each is linked with C1orf216 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf216-to-partner and partner-to-C1orf216 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myocytes grouped by C1orf216-low versus C1orf216-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf216→partner) and Y-score (partner→C1orf216) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Myocytes →	+0.050	+3.212	.005	.010	3	1
UCEC	Basophils →	+0.240	+3.169	.010	.020	3	1
UCEC	Endothelial cells →	-0.050	-3.127	.016	.020	2	1
UCEC	pro B-cells →	+0.146	+3.016	.014	.019	2	1
UCEC	lymphatic Endothelial cells →	-0.029	-3.116	.027	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Myocytes by C1orf216 expression — UCEC

Explore this box plot interactively →