C1orf216

Across TCGA cell cohorts, C1orf216 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,354 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C1orf216-associated GO terms across cancer lineages are Cell division, Microtubule cytoskeleton organization involved in mitosis, and Chromosome segregation. Each is linked with C1orf216 in more than 13 cancer types. Because this analysis shows association rather than direction, both C1orf216-to-partner and partner-to-C1orf216 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell division grouped by C1orf216-low versus C1orf216-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf216→partner) and Y-score (partner→C1orf216) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cell division →	+0.083	+0.901	<.001	<.001	3	14
OVARY	Microtubule cytoskeleton organization involved in mitosis →	+0.083	+1.072	<.001	.002	3	14
PANCREAS	Chromosome segregation →	+0.103	+0.954	<.001	.001	3	14
PANCREAS	Microtubule polymerization →	+0.100	+1.103	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Mitotic cytokinesis →	+0.084	+0.826	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Regulation of cytokinesis →	+0.075	+1.044	.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,354 associations by consensus.

Cell division by C1orf216 expression — BREAST

Explore this box plot interactively →