C1orf216

Across TCGA cell cohorts, C1orf216 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C1orf216-associated genes across cancer lineages are TTLL8 and OR52H1. Each is linked with C1orf216 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf216-to-partner and partner-to-C1orf216 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TTLL8 grouped by C1orf216-low versus C1orf216-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf216→partner) and Y-score (partner→C1orf216) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TTLL8 →	+0.004	+4.437	<.001	.004	3	1
LARGE_INTESTINE	OR52H1 →	+0.033	+4.347	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

TTLL8 by C1orf216 expression — LARGE_INTESTINE

Explore this box plot interactively →