C1orf198

Across TCGA cell cohorts, C1orf198 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,843 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C1orf198-associated GO terms across cancer lineages are Vesicle targeting, Regulation of RNA export from nucleus, and Cytoskeleton-dependent cytokinesis. Each is linked with C1orf198 in more than 10 cancer types. Because this analysis shows association rather than direction, both C1orf198-to-partner and partner-to-C1orf198 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle targeting grouped by C1orf198-low versus C1orf198-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf198→partner) and Y-score (partner→C1orf198) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Vesicle targeting →	+0.052	+1.141	.006	.001	3	11
OVARY	Regulation of RNA export from nucleus →	+0.105	+1.437	.001	<.001	3	10
SKIN	Cytoskeleton-dependent cytokinesis →	+0.053	+1.114	.001	.001	2	11
UPPER_AERODIGESTIVE_TRACT	Regulation of G0 to G1 transition →	+0.097	+1.155	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of gene expression, epigenetic →	+0.089	+0.855	.001	<.001	3	9
LUNG_SCLC	Regulation of G1/S transition of mitotic cell cycle →	+0.066	+1.354	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,843 associations by consensus.

Vesicle targeting by C1orf198 expression — LIVER

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