C1orf189

Across TCGA pan-cancer cohorts, C1orf189 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated C1orf189 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher C1orf189 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated C1orf189 expression acts as an unfavorable survival marker.

THYM and COAD are the cancer types where C1orf189 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	DFS	Median	All	0.123	0.871	<.001	12	view →
COAD	DFS	Median	All	0.175	0.691	.002	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

C1orf189–THYM (DFS)

Open the THYM breakdown →