Across TCGA patient cohorts, C1orf174 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,648 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C1orf174-associated proteins across cancer lineages are LRRC47, SSRP1, and MCM4. Each is linked with C1orf174 in more than 6 cancer types. Because this analysis shows association rather than direction, both C1orf174-to-partner and partner-to-C1orf174 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf174→partner) and Y-score (partner→C1orf174) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LRRC47 →	+0.339	+0.497	<.001	<.001	3	7
LSCC	SSRP1 →	+0.446	+0.489	<.001	<.001	3	6
LSCC	MCM4 →	+0.705	+0.497	<.001	<.001	3	6
LSCC	MCM6 →	+0.723	+0.503	<.001	<.001	3	6
GBM	UHRF1 →	+0.590	+0.331	<.001	.001	3	5
LSCC	RFC3 →	+0.307	+0.461	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,648 associations by consensus.

Exploration

C1orf174 survival (RNA) · tumor vs normal (RNA) · all C1orf174 data types