Across TCGA cell cohorts, C1orf174 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,966 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C1orf174-associated GO terms across cancer lineages are DNA replication checkpoint signaling, Centrosome duplication, and DNA replication initiation. Each is linked with C1orf174 in more than 15 cancer types. Because this analysis shows association rather than direction, both C1orf174-to-partner and partner-to-C1orf174 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf174→partner) and Y-score (partner→C1orf174) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication checkpoint signaling →	+0.172	+0.588	.003	.003	3	16
BONE	Centrosome duplication →	+0.117	+0.643	<.001	<.001	3	15
BONE	DNA replication initiation →	+0.127	+0.433	.002	.004	3	15
BONE	Response to methionine →	+0.115	+0.657	<.001	<.001	3	14
BONE	Regulation of telomerase RNA localization to Cajal body →	+0.119	+0.595	<.001	<.001	3	14
BONE	Cellular response to methionine →	+0.115	+0.657	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,966 associations by consensus.

Exploration

C1orf174 survival (RNA) · tumor vs normal (RNA) · all C1orf174 data types