C1orf167

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C1orf167 mutation is significantly associated with the drug of many other genes, with 41 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C1orf167-associated genes across cancer lineages are OTX015, 50869, and Sinularin. Each is linked with C1orf167 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf167-to-partner and partner-to-C1orf167 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf167→partner) and Y-score (partner→C1orf167) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOTX015 →+0.519+2.646.039.04731
LARGE_INTESTINE50869 →+0.481+2.649.022.04631
LARGE_INTESTINESinularin →+0.319+2.777.043.03831
LARGE_INTESTINESabutoclax →+0.602+2.769.003.04031
LARGE_INTESTINECX-5461 →+0.837+2.652.003.04531
LARGE_INTESTINET0901317 →+0.305+2.722.026.04031
Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

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