C1orf162

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, C1orf162 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C1orf162 data layer compared with 21 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in sarcoma (SARC), where higher C1orf162 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated C1orf162 expression acts as an unfavorable survival marker.

SARC, LUSC, and SKCM are the cancer types where C1orf162 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SARCDFSMedianAll0.1210.611.0416view →
LUSCDFSMedianII,III,IV0.1350.663.0156view →
SKCMDFSMedianAll0.1920.757.0226view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

C1orf162–SARC (DFS)

Kaplan–Meier survival curve for C1orf162 mutant vs wild-type samples in SARC.

Open the SARC breakdown →

Exploration