C1orf159

Across TCGA patient cohorts, C1orf159 mutation is significantly associated with the RNA expression of many other genes, with 241 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf159-associated genes across cancer lineages are CDRT15P7, RNU1-105P, and MIR1305. Each is linked with C1orf159 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf159-to-partner and partner-to-C1orf159 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDRT15P7 grouped by C1orf159-low versus C1orf159-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf159→partner) and Y-score (partner→C1orf159) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CDRT15P7 →	+0.132	+6.199	<.001	.001	3	2
SKCM	RNU1-105P →	+0.416	+5.594	<.001	.004	3	2
SKCM	MIR1305 →	+1.023	+5.037	<.001	.009	3	2
SKCM	UBE2D3P4 →	+0.168	+5.680	<.001	.003	3	2
BLCA	RNA5SP521 →	+0.457	+4.973	<.001	.009	3	2
UCEC	RNU4-85P →	+0.270	+2.870	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 241 associations by consensus.

CDRT15P7 by C1orf159 expression — SKCM

Explore this box plot interactively →