C1orf159

Across TCGA cell cohorts, C1orf159 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,802 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C1orf159-associated GO terms across cancer lineages are Mitotic chromosome condensation, Negative regulation of transcription initiation by RNA polymerase II, and Pre-mRNA catabolic process. Each is linked with C1orf159 in more than 12 cancer types. Because this analysis shows association rather than direction, both C1orf159-to-partner and partner-to-C1orf159 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic chromosome condensation grouped by C1orf159-low versus C1orf159-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf159→partner) and Y-score (partner→C1orf159) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitotic chromosome condensation →	+0.156	+0.910	<.001	<.001	3	13
BONE	Negative regulation of transcription initiation by RNA polymerase II →	+0.114	+0.843	<.001	<.001	3	13
BONE	Pre-mRNA catabolic process →	+0.229	+1.021	<.001	<.001	3	13
BONE	Negative regulation of DNA-templated transcription initiation →	+0.114	+0.843	<.001	<.001	3	13
BONE	Signal transduction in response to DNA damage →	+0.073	+1.037	<.001	<.001	3	12
BONE	Establishment of spindle localization →	+0.133	+1.432	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,802 associations by consensus.

Mitotic chromosome condensation by C1orf159 expression — BONE

Explore this box plot interactively →