Q-omics provides the consensus-scored C1orf147 profile across patient tissues and cancer cell-line models. C1orf147 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, C1orf147 is differentially expressed in 12, with the highest sampling consensus in KIRC. Additionally, C1orf147 RNA expression shows 17,914 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight UVM, and KIRC as cancer lineages where C1orf147 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for C1orf147 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes C1orf147 survival associations across molecular data types. C1orf147 RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible C1orf147 RNA expression–survival associations across cancer types. High C1orf147 expression shows unfavorable associations in UVM, KIRC, KICH, LGG and LIHC, but favorable associations in HNSC. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for C1orf147 RNA expression.
This table summarizes C1orf147 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for C1orf147. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. C1orf147 shows higher tumor expression in KIRC, COAD, KIRP, LUAD, STAD and LIHC. The KIRC box plot shows higher C1orf147 RNA expression in tumor versus normal tissue (log2 FC = +0.121, t-test p < 0.001).
This table shows molecular features associated with C1orf147 in patient tissues and cancer cell lines. In patient samples, C1orf147 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, C1orf147 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LARGE_INTESTINE, while CRISPR and shRNA rows add functional-dependency signals in OVARY.
