Across TCGA patient cohorts, C1orf146 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,187 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C1orf146-associated proteins across cancer lineages are GATAD2B_S334, IRF2BP1_S186, and KMT2A_T3028. Each is linked with C1orf146 in more than 5 cancer types. Because this analysis shows association rather than direction, both C1orf146-to-partner and partner-to-C1orf146 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf146→partner) and Y-score (partner→C1orf146) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GATAD2B_S334 →	+0.583	+0.260	<.001	.002	3	6
PDAC	IRF2BP1_S186 →	+0.761	+0.383	<.001	<.001	3	5
UCEC	KMT2A_T3028 →	+0.560	+0.549	<.001	<.001	3	5
GBM	PLS3_S339 →	-0.632	-0.530	<.001	<.001	3	5
COAD	POLR1A_T357 →	-0.925	-0.236	<.001	<.001	3	5
HNSC	PRKAB2_S158 →	-0.816	-0.338	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,187 associations by consensus.

Exploration

C1orf146 survival (RNA) · tumor vs normal (RNA) · all C1orf146 data types