Across TCGA patient cohorts, C1orf146 mutation is significantly associated with the RNA expression of many other genes, with 84 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf146-associated genes across cancer lineages are OFD1P3Y, IGHD6-19, and RNU6-492P. Each is linked with C1orf146 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf146-to-partner and partner-to-C1orf146 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf146→partner) and Y-score (partner→C1orf146) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OFD1P3Y →	+0.156	+6.018	<.001	.002	3	2
UCEC	IGHD6-19 →	+0.879	+3.835	<.001	<.001	3	2
HNSC	RNU6-492P →	+0.478	+7.954	<.001	.008	3	1
HNSC	RNU4-26P →	+0.268	+7.954	<.001	.008	3	1
BLCA	MIR548AQ →	+0.526	+5.899	<.001	.002	3	1
BLCA	F8A2 →	+0.032	+4.973	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 84 associations by consensus.

Exploration

C1orf146 survival (RNA) · tumor vs normal (RNA) · all C1orf146 data types