C1orf131

Across TCGA patient cohorts, C1orf131 protein abundance is significantly associated with the RNA expression of many other genes, with 11,466 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C1orf131-associated genes across cancer lineages are MRPL51, MCM3, and MCM10. Each is linked with C1orf131 in more than 4 cancer types. Because this analysis shows association rather than direction, both C1orf131-to-partner and partner-to-C1orf131 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf131 versus MRPL51 in HNSC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf131→partner) and Y-score (partner→C1orf131) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MRPL51 →	+0.843	+0.562	.002	.006	3	5
LSCC	MCM3 →	+0.683	+0.350	<.001	<.001	3	5
LSCC	MCM10 →	+1.195	+0.481	<.001	<.001	3	5
LSCC	PPM1G →	+0.500	+0.422	<.001	<.001	3	4
LSCC	IL1RL1 →	-0.990	-0.473	<.001	<.001	3	4
UCEC	CDC20 →	+1.209	+0.271	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,466 associations by consensus.

C1orf131 vs MRPL51 — HNSC

Explore this scatter interactively →