C1orf131

Across TCGA patient cohorts, C1orf131 mutation is significantly associated with the RNA expression of many other genes, with 1,507 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf131-associated genes across cancer lineages are LSP1P1, ABHD3, and SMIM10L2A. Each is linked with C1orf131 in more than 2 cancer types. Because this analysis shows association rather than direction, both C1orf131-to-partner and partner-to-C1orf131 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LSP1P1 grouped by C1orf131-low versus C1orf131-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf131→partner) and Y-score (partner→C1orf131) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LSP1P1 →	+0.546	+4.543	.002	.005	3	3
SKCM	ABHD3 →	+0.661	+2.591	.001	.006	3	2
UCEC	SMIM10L2A →	-0.538	-2.767	.009	.003	3	2
BLCA	RPL23P4 →	+0.119	+3.680	<.001	.009	3	2
UCEC	OBSCN →	-0.623	-2.247	.004	.002	3	2
UCEC	CARD19 →	+0.330	+2.280	.006	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,507 associations by consensus.

LSP1P1 by C1orf131 expression — COAD

Explore this box plot interactively →