C1orf116

Across TCGA patient cohorts, C1orf116 protein abundance is significantly associated with the RNA expression of many other genes, with 14,980 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible C1orf116-associated genes across cancer lineages are MACC1, ADGRF1, and PTK6. Each is linked with C1orf116 in more than 7 cancer types. Because this analysis shows association rather than direction, both C1orf116-to-partner and partner-to-C1orf116 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf116 versus MACC1 in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf116→partner) and Y-score (partner→C1orf116) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MACC1 →	+1.167	+1.024	.003	.001	3	8
LUAD	ADGRF1 →	+2.556	+1.002	<.001	<.001	3	7
UCEC	PTK6 →	+1.176	+0.824	<.001	<.001	3	6
HNSC	GPRC5A →	+1.617	+0.784	<.001	<.001	3	6
HNSC	MPZL2 →	+0.963	+0.664	<.001	<.001	2	7
OV	SPATS2 →	-0.736	-0.823	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,980 associations by consensus.

C1orf116 vs MACC1 — OV

Explore this scatter interactively →