C1orf116

Across TCGA cell cohorts, C1orf116 RNA expression is significantly associated with the RNA expression of many other genes, with 9,129 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C1orf116-associated genes across cancer lineages are SH2D3A, MAL2, and MPZL2. Each is linked with C1orf116 in more than 13 cancer types. Because this analysis shows association rather than direction, both C1orf116-to-partner and partner-to-C1orf116 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf116 versus SH2D3A in URINARY_TRACT, with a Pearson correlation of 0.89.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf116→partner) and Y-score (partner→C1orf116) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	SH2D3A →	+2.515	+2.654	<.001	<.001	3	14
URINARY_TRACT	MAL2 →	+5.238	+3.606	<.001	<.001	3	13
URINARY_TRACT	MPZL2 →	+4.730	+3.461	<.001	<.001	3	13
URINARY_TRACT	GJB3 →	+3.002	+2.510	<.001	<.001	3	12
URINARY_TRACT	SERPINB5 →	+3.758	+2.932	<.001	<.001	3	12
URINARY_TRACT	ADGRF1 →	+4.283	+4.364	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,129 associations by consensus.

C1orf116 vs SH2D3A — URINARY_TRACT

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