C1orf116

Across TCGA cell cohorts, C1orf116 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,437 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C1orf116-associated GO terms across cancer lineages are Negative regulation of supramolecular fiber organization, Cell-substrate junction assembly, and Mammary gland development. Each is linked with C1orf116 in more than 11 cancer types. Because this analysis shows association rather than direction, both C1orf116-to-partner and partner-to-C1orf116 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of supramolecular fiber organization grouped by C1orf116-low versus C1orf116-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf116→partner) and Y-score (partner→C1orf116) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of supramolecular fiber organization →	+0.079	+2.488	<.001	.002	3	12
LUNG_NSCLC_LUAD	Cell-substrate junction assembly →	+0.207	+2.920	<.001	<.001	3	12
URINARY_TRACT	Mammary gland development →	+0.131	+3.760	<.001	<.001	3	12
LUNG_NSCLC_LUAD	Cell-substrate junction organization →	+0.189	+2.623	<.001	<.001	3	11
OVARY	Positive regulation of sodium ion transmembrane transport →	+0.328	+2.461	<.001	<.001	3	11
LUNG_SCLC	Regulation of inner ear receptor cell differentiation →	+1.154	+1.839	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,437 associations by consensus.

Negative regulation of supramolecular fiber organization by C1orf116 expression — STOMACH

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