C1orf112

Across TCGA patient cohorts, C1orf112 mutation is significantly associated with the RNA expression of many other genes, with 3,415 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf112-associated genes across cancer lineages are RNA5SP432, ASB16-AS1, and ALDOA. Each is linked with C1orf112 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf112-to-partner and partner-to-C1orf112 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP432 grouped by C1orf112-low versus C1orf112-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf112→partner) and Y-score (partner→C1orf112) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5SP432 →	+0.390	+4.118	<.001	.004	3	2
UCEC	ASB16-AS1 →	+0.362	+3.098	<.001	<.001	3	2
UCEC	ALDOA →	+0.403	+2.415	.001	<.001	3	2
UCEC	MIDN →	+0.316	+4.000	.005	<.001	3	2
UCEC	SLC25A33 →	+0.590	+2.424	<.001	<.001	3	2
UCEC	TALDO1 →	+0.437	+1.698	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,415 associations by consensus.

RNA5SP432 by C1orf112 expression — SKCM

Explore this box plot interactively →