C1orf112

Across TCGA cell cohorts, C1orf112 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,124 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C1orf112-associated GO terms across cancer lineages are Replication fork processing, Regulation of sister chromatid segregation, and Mitotic DNA replication checkpoint signaling. Each is linked with C1orf112 in more than 19 cancer types. Because this analysis shows association rather than direction, both C1orf112-to-partner and partner-to-C1orf112 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Replication fork processing grouped by C1orf112-low versus C1orf112-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf112→partner) and Y-score (partner→C1orf112) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Replication fork processing →	+0.154	+1.386	<.001	<.001	3	20
BLOOD_Myeloma	Regulation of sister chromatid segregation →	+0.130	+1.273	<.001	<.001	3	20
BONE	Mitotic DNA replication checkpoint signaling →	+0.269	+1.484	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Mitotic G2/M transition checkpoint →	+0.134	+1.507	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication maintenance of fidelity →	+0.133	+1.347	<.001	<.001	3	20
KIDNEY	Metaphase chromosome alignment →	+0.142	+1.312	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,124 associations by consensus.

Replication fork processing by C1orf112 expression — BONE

Explore this box plot interactively →