C1orf109

Across TCGA patient cohorts, C1orf109 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,936 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C1orf109-associated proteins across cancer lineages are NASP, MCM4, and SSRP1. Each is linked with C1orf109 in more than 7 cancer types. Because this analysis shows association rather than direction, both C1orf109-to-partner and partner-to-C1orf109 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf109 versus NASP in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf109→partner) and Y-score (partner→C1orf109) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NASP →	+0.462	+0.258	<.001	<.001	3	8
LUAD	MCM4 →	+0.673	+0.292	<.001	.006	3	7
GBM	SSRP1 →	+0.395	+0.234	<.001	<.001	3	7
UCEC	CDC73 →	+0.307	+0.569	<.001	<.001	3	7
UCEC	HAT1 →	+0.430	+0.484	<.001	.001	3	7
OV	PPIE →	+0.414	+0.401	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,936 associations by consensus.

C1orf109 vs NASP — GBM

Explore this scatter interactively →