C1orf109

Across TCGA patient cohorts, C1orf109 protein abundance is significantly associated with the RNA expression of many other genes, with 5,005 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C1orf109-associated genes across cancer lineages are MCAM, ABCC5, and PDLIM7. Each is linked with C1orf109 in more than 2 cancer types. Because this analysis shows association rather than direction, both C1orf109-to-partner and partner-to-C1orf109 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1orf109 versus MCAM in CCRCC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf109→partner) and Y-score (partner→C1orf109) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MCAM →	+0.836	+0.347	.003	.005	3	3
HNSC	ABCC5 →	-1.426	-0.196	<.001	.004	3	2
GBM	PDLIM7 →	+0.565	+0.236	.001	.003	3	2
CCRCC	LINC00621 →	-2.223	-0.355	.009	.007	3	2
OV	CTSA →	-0.557	-0.475	.007	.003	3	2
BRCA	PYGL →	+0.790	+0.303	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,005 associations by consensus.

C1orf109 vs MCAM — CCRCC

Explore this scatter interactively →