C1orf109

Across TCGA cell cohorts, C1orf109 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,137 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C1orf109-associated GO terms across cancer lineages are Nuclear pore complex assembly, Positive regulation of cell cycle process, and Sister chromatid segregation. Each is linked with C1orf109 in more than 16 cancer types. Because this analysis shows association rather than direction, both C1orf109-to-partner and partner-to-C1orf109 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore complex assembly grouped by C1orf109-low versus C1orf109-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf109→partner) and Y-score (partner→C1orf109) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Nuclear pore complex assembly →	+0.159	+1.268	<.001	<.001	3	17
BREAST	Positive regulation of cell cycle process →	+0.090	+0.837	<.001	.001	3	17
BONE	Sister chromatid segregation →	+0.130	+0.924	.005	<.001	3	17
BONE	Positive regulation of nuclear cell cycle DNA replication →	+0.189	+1.072	<.001	<.001	3	16
PANCREAS	DNA replication checkpoint signaling →	+0.191	+0.984	<.001	<.001	3	16
SOFT_TISSUE	Positive regulation of cell cycle →	+0.097	+0.812	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,137 associations by consensus.

Nuclear pore complex assembly by C1orf109 expression — LARGE_INTESTINE

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