C1orf100

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C1orf100 mutation is significantly associated with the RNA expression of many other genes, with 823 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1orf100-associated genes across cancer lineages are OR9Q2, IGHD3-16, and CRYBB2P1. Each is linked with C1orf100 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1orf100-to-partner and partner-to-C1orf100 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR9Q2 grouped by C1orf100-low versus C1orf100-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1orf100→partner) and Y-score (partner→C1orf100) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADOR9Q2 →+0.047+4.721<.001.00432
COADIGHD3-16 →+1.532+3.884.005.00432
UCECCRYBB2P1 →+0.534+2.721.003.00331
UCECGGA1 →+0.358+2.721.007.00331
UCECJOSD1 →+0.489+3.807.006<.00131
UCECPOLDIP3 →+0.520+3.625.005.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 823 associations by consensus.

OR9Q2 by C1orf100 expression — COAD

Box plot of OR9Q2 in C1orf100-low vs C1orf100-high samples in COAD.

Explore this box plot interactively →

Exploration