C1RL

Across TCGA patient cohorts, C1RL RNA expression is significantly associated with the protein abundance of many other proteins, with 13,952 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C1RL-associated proteins across cancer lineages are TPI1, STRBP, and ETV6. Each is linked with C1RL in more than 5 cancer types. Because this analysis shows association rather than direction, both C1RL-to-partner and partner-to-C1RL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1RL versus TPI1 in OV, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1RL→partner) and Y-score (partner→C1RL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TPI1 →	+0.447	+0.805	<.001	<.001	3	6
LSCC	STRBP →	-0.543	-0.549	.001	<.001	3	5
LSCC	ETV6 →	+0.314	+0.461	.001	<.001	3	5
CCRCC	PLOD2 →	+1.005	+0.670	<.001	<.001	3	5
OV	LPCAT3 →	+0.477	+0.650	.003	.004	3	5
GBM	NNMT →	+0.930	+0.593	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,952 associations by consensus.

C1RL vs TPI1 — OV

Explore this scatter interactively →