C1RL

Across TCGA patient cohorts, C1RL mutation is significantly associated with the RNA expression of many other genes, with 677 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible C1RL-associated genes across cancer lineages are RNU1-140P, LINC02103, and APOBEC3AP1. Each is linked with C1RL in more than 1 cancer types. Because this analysis shows association rather than direction, both C1RL-to-partner and partner-to-C1RL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-140P grouped by C1RL-low versus C1RL-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1RL→partner) and Y-score (partner→C1RL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU1-140P →	+0.207	+6.902	<.001	<.001	3	2
LIHC	LINC02103 →	+0.203	+5.355	.005	.005	3	2
COAD	APOBEC3AP1 →	+0.599	+4.666	<.001	.005	3	2
UCEC	MIR8082 →	+0.336	+2.424	<.001	.005	3	2
UCEC	CIDECP1 →	+0.309	+3.475	.008	.002	3	2
UCEC	RN7SKP19 →	+0.109	+3.928	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 677 associations by consensus.

RNU1-140P by C1RL expression — LIHC

Explore this box plot interactively →