C1R

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C1R RNA expression is significantly associated with the protein abundance of many other proteins, with 26,449 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C1R-associated proteins across cancer lineages are TBC1D2B, WIPF1, and NNMT. Each is linked with C1R in more than 9 cancer types. Because this analysis shows association rather than direction, both C1R-to-partner and partner-to-C1R results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1R versus TBC1D2B in UCEC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1R→partner) and Y-score (partner→C1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTBC1D2B →+0.398+1.061<.001<.001310
OVWIPF1 →+0.425+1.149.002<.00139
GBMNNMT →+1.300+1.037<.001<.00139
GBMLCP1 →+0.778+1.244<.001<.00139
GBMGBP2 →+0.753+1.246<.001<.00139
OVCNN2 →+0.934+1.136<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 26,449 associations by consensus.

C1R vs TBC1D2B — UCEC

Per-sample scatter of C1R vs TBC1D2B in UCEC (Pearson r = 0.40).

Explore this scatter interactively →

Exploration