C1R

Across TCGA patient cohorts, C1R protein abundance is significantly associated with the RNA expression of many other genes, with 18,152 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C1R-associated genes across cancer lineages are MYL9, CRISPLD2, and SERPINE1. Each is linked with C1R in more than 9 cancer types. Because this analysis shows association rather than direction, both C1R-to-partner and partner-to-C1R results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1R versus MYL9 in COAD, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1R→partner) and Y-score (partner→C1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MYL9 →	+1.362	+0.482	<.001	<.001	3	10
OV	CRISPLD2 →	+1.581	+0.712	<.001	<.001	3	10
OV	SERPINE1 →	+1.704	+0.635	<.001	<.001	3	10
OV	FN1 →	+2.316	+0.733	<.001	<.001	3	10
OV	PLAU →	+1.420	+0.689	<.001	<.001	3	10
OV	COL5A1 →	+2.095	+0.673	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,152 associations by consensus.

C1R vs MYL9 — COAD

Explore this scatter interactively →