Across TCGA pan-cancer cohorts, C1QTNF9B Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated C1QTNF9B data layer compared with 20 for mass-spec protein.
The strongest signal is observed in brain lower grade glioma (LGG), where higher C1QTNF9B Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated C1QTNF9B expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.
LGG and STAD are the cancer types where C1QTNF9B Mutation most reproducibly stratifies survival.