C1QTNF7

Across TCGA pan-cancer cohorts, C1QTNF7 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated C1QTNF7 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher C1QTNF7 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated C1QTNF7 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

HNSC, UCEC, and PDAC are the cancer types where C1QTNF7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.134	1.000	.038	48	view →
UCEC	OS	Median	II,III,IV	0.495	0.911	.044	4	view →
PDAC	DFS	Median	All	0.629	0.283	.015	2	view →
LSCC	DFS	Median	II,III,IV	0.343	0.825	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

C1QTNF7–HNSC (OS)

Open the HNSC breakdown →