C1QTNF7

Across TCGA patient cohorts, C1QTNF7 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1QTNF7-associated genes across cancer lineages are EGFR_pY1068, STAT3_pY705, and p38-MAPK_pT180_Y182. Each is linked with C1QTNF7 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QTNF7-to-partner and partner-to-C1QTNF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by C1QTNF7-low versus C1QTNF7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QTNF7→partner) and Y-score (partner→C1QTNF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.309	-3.169	.024	.020	3	1
UCEC	STAT3_pY705 →	-0.712	-3.159	<.001	.019	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.609	-3.156	.013	.020	2	1
UCEC	ATM →	-1.003	-3.169	<.001	.020	1	2
UCEC	Gab2 →	+0.500	+3.169	.010	.020	1	1
UCEC	mTOR →	-0.216	-3.169	.014	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

EGFR_pY1068 by C1QTNF7 expression — UCEC

Explore this box plot interactively →