C1QTNF4

Across TCGA cell cohorts, C1QTNF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,296 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C1QTNF4-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Regulation of syncytium formation by plasma membrane fusion, and Protein sumoylation. Each is linked with C1QTNF4 in more than 8 cancer types. Because this analysis shows association rather than direction, both C1QTNF4-to-partner and partner-to-C1QTNF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by C1QTNF4-low versus C1QTNF4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QTNF4→partner) and Y-score (partner→C1QTNF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.142	+0.095	.007	.005	3	8
BONE	Regulation of syncytium formation by plasma membrane fusion →	+0.076	+0.396	.002	<.001	3	8
OVARY	Protein sumoylation →	+0.048	+0.213	<.001	.008	3	8
BONE	Negative regulation of DNA-templated transcription, elongation →	+0.103	+0.366	.003	<.001	3	8
BREAST	Regulation of myoblast fusion →	+0.084	+0.157	<.001	.002	2	9
LUNG_SCLC	Peptidyl-amino acid modification →	+0.038	+0.877	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,296 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by C1QTNF4 expression — OESOPHAGUS

Explore this box plot interactively →