C1QTNF4

Across TCGA cell cohorts, C1QTNF4 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C1QTNF4-associated genes across cancer lineages are GRM4, KCNK17, and NAT8. Each is linked with C1QTNF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QTNF4-to-partner and partner-to-C1QTNF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GRM4 grouped by C1QTNF4-low versus C1QTNF4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QTNF4→partner) and Y-score (partner→C1QTNF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GRM4 →	+1.150	+3.491	<.001	.004	3	1
LARGE_INTESTINE	KCNK17 →	+0.062	+3.906	<.001	.002	3	1
LARGE_INTESTINE	NAT8 →	+0.759	+3.706	<.001	.002	3	1
LARGE_INTESTINE	C1QL2 →	+0.004	+3.514	.006	.001	3	1
LARGE_INTESTINE	OR10W1 →	+0.015	+4.392	<.001	<.001	3	1
LARGE_INTESTINE	TAFA1 →	+0.234	+3.103	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

GRM4 by C1QTNF4 expression — LARGE_INTESTINE

Explore this box plot interactively →