C1QTNF3

Across TCGA pan-cancer cohorts, C1QTNF3 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated C1QTNF3 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher C1QTNF3 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated C1QTNF3 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC, PDAC, and LSCC are the cancer types where C1QTNF3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.940	0.746	.003	36	view →
PDAC	DFS	Median	III,IV	0.116	0.542	.001	23	view →
LSCC	DFS	Quartile	II,III,IV	0.601	0.931	.031	3	view →
LUAD	DFS	Quartile	All	0.557	0.839	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

C1QTNF3–CCRCC (OS)

Open the CCRCC breakdown →