C1QTNF2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C1QTNF2 mutation is significantly associated with the RNA expression of many other genes, with 2,402 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C1QTNF2-associated genes across cancer lineages are NPLP1, WASHC3P1, and LINC01784. Each is linked with C1QTNF2 in more than 2 cancer types. Because this analysis shows association rather than direction, both C1QTNF2-to-partner and partner-to-C1QTNF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPLP1 grouped by C1QTNF2-low versus C1QTNF2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QTNF2→partner) and Y-score (partner→C1QTNF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCNPLP1 →+0.128+3.776<.001.00733
STADWASHC3P1 →+0.390+4.991<.001<.00133
STADLINC01784 →+0.248+3.682<.001.00533
STADRNA5SP436 →+0.559+4.151<.001.00133
STADRNU6-557P →+1.025+4.433<.001.00133
STADIGHVII-44-2 →+0.206+3.505<.001.00833
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,402 associations by consensus.

NPLP1 by C1QTNF2 expression — LIHC

Box plot of NPLP1 in C1QTNF2-low vs C1QTNF2-high samples in LIHC.

Explore this box plot interactively →

Exploration