C1QTNF2

Across TCGA cell cohorts, C1QTNF2 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C1QTNF2-associated genes across cancer lineages are OR12D3, NLRP8, and BPY2. Each is linked with C1QTNF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QTNF2-to-partner and partner-to-C1QTNF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR12D3 grouped by C1QTNF2-low versus C1QTNF2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QTNF2→partner) and Y-score (partner→C1QTNF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR12D3 →	+0.035	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	NLRP8 →	+0.054	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	BPY2 →	+0.006	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	BPY2B →	+0.006	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	BPY2C →	+0.006	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR12D1 →	+0.042	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

OR12D3 by C1QTNF2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →