C1QTNF1-AS1

Across TCGA pan-cancer cohorts, C1QTNF1-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of C1QTNF1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where C1QTNF1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types C1QTNF1-AS1 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KICH, KIRC, and BRCA are the cancer types where C1QTNF1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C1QTNF1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	II,III,IV	−0.505	<.001	10	view →
KIRC	Male	III,IV	+0.742	<.001	8	view →
BRCA	All	III,IV	−0.448	<.001	8	view →
LUAD	All	III,IV	−0.448	<.001	8	view →
LIHC	All	All	+0.622	<.001	5	view →
STAD	Male	III,IV	+0.425	.030	3	view →
THCA	All	All	+0.141	.002	3	view →
LUSC	Female	All	−0.438	.004	2	view →
PRAD	All	All	−0.241	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

C1QTNF1-AS1–KICH

Open the KICH breakdown →