Across TCGA pan-cancer cohorts, C1QL4 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated C1QL4 data layer compared with 22 for mass-spec protein and 3 for mutation status.
The strongest signal is observed in glioblastoma multiforme (GBM), where higher C1QL4 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated C1QL4 expression acts as an unfavorable survival marker.
GBM are the cancer types where C1QL4 mass-spec protein most reproducibly stratifies survival.