Across TCGA cell cohorts, C1QL4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C1QL4-associated genes across cancer lineages are ZBBX, BLID, and CHAT. Each is linked with C1QL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QL4-to-partner and partner-to-C1QL4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QL4→partner) and Y-score (partner→C1QL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZBBX →	+0.118	+3.658	<.001	.005	3	1
LARGE_INTESTINE	BLID →	+0.388	+4.669	<.001	<.001	3	1
LARGE_INTESTINE	CHAT →	+0.027	+3.688	.002	.002	3	1
LARGE_INTESTINE	GLIS1 →	+0.330	+3.669	<.001	.008	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

C1QL4 survival (RNA) · tumor vs normal (RNA) · all C1QL4 data types